BDBM480406 (R)-3-(tert-butyl)-N-(1-fluoro-2-(4-((1-methyl-1H-pyrazol-3-yl)amino)-1,3,5-triazin-2-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl)-1,2,4-oxadiazole-5-carboxamide ::US10899753, Example 89

SMILES Cn1ccc(Nc2ncnc(n2)-c2ccc3[C@@H](CCCCc3c2F)NC(=O)c2nc(no2)C(C)(C)C)n1

InChI Key InChIKey=HPCNLUGLZBINSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480406   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM480406((R)-3-(tert-butyl)-N-(1-fluoro-2-(4-((1-methyl-1H-...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
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Date in BDB:
8/15/2021
Entry Details
US Patent