BDBM480425 N-(3-fluoro-2-methyl-4-(4-((1-methyl-1H-pyrazol-3-yl)amino)-1,3,5-triazin-2-yl)benzyl)-5-(1-methylcyclopropyl)-1,2,4-oxadiazole-3-carboxamide ::US10899753, Example 113

SMILES Cc1c(CNC(=O)c2noc(n2)C2(C)CC2)ccc(c1F)-c1ncnc(Nc2ccn(C)n2)n1

InChI Key InChIKey=HBFHOUNYRDIUQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480425   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM480425(N-(3-fluoro-2-methyl-4-(4-((1-methyl-1H-pyrazol-3-...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent