BDBM481148 6-((5R,8S)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro-5,8-methanoimidazo[1,2-a]pyridin-3-yl)quinoline-4-carboxamide 1-2::US10906905, Example 1-2

SMILES Cc1cccc(n1)-c1nc2[C@H]3CC[C@H](C3)n2c1-c1ccc2nccc(C(N)=O)c2c1

InChI Key InChIKey=CSMOUVFWIWCQLV-JKSUJKDBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481148   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM481148(6-((5R,8S)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrah...)
Affinity DataIC50:  16nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent