BDBM481158 US10906900, Reference 25b

SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1ccsc1

InChI Key InChIKey=SPYYWCDGZNJHNH-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 481158   

TargetAlpha-synuclein(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481158(US10906900, Reference 25b)
Affinity DataKd:  0.730nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
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TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481158(US10906900, Reference 25b)
Affinity DataKd:  4.27nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent