BDBM481186 US10906905, Example 9-2
SMILES NC(=O)c1nnc2ccc(cn12)-c1c(nc2[C@H]3CC[C@H](C3)n12)-c1ccc(F)cn1
InChI Key InChIKey=KZNQXFBFJRDXTF-GXFFZTMASA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 481186
Affinity DataIC50: 13nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
Affinity DataIC50: 2.46E+3nMAssay Description:p38α kinase assay kit (V9591, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in the...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Jiangsu Hengrui Medicine
US Patent
Jiangsu Hengrui Medicine
US Patent
Affinity DataIC50: 1.35E+3nMAssay Description:VEGFR2: Z′-LYTE® Kinase Assay Kit—Tyrosine 1 Peptide (PV3190, Invitrogen) was used to assay enzyme activity. 5 μl of recombinant human VEG...More data for this Ligand-Target Pair