BDBM481196 US10906905, Example 35-2

SMILES Cc1cccc(n1)-c1nn2[C@H]3CC[C@H](C3)c2c1-c1ccnc2ccc(cc12)C(N)=O

InChI Key InChIKey=HPBBGUGOYYVTHJ-ZBFHGGJFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481196   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM481196(US10906905, Example 35-2)
Affinity DataIC50:  25nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent