BDBM481203 6-((5R,8S)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrahydro-5,8-methanoimidazo[1,2-a]pyridin-3-yl)[1,2,4]triazolo[4,3-a]pyridine-3-carboxamide 2-2::US10906905, Example 2-2

SMILES Cc1cccc(n1)-c1nc2[C@H]3CC[C@H](C3)n2c1-c1ccc2nnc(C(N)=O)n2c1

InChI Key InChIKey=BKVNNKVIKPHFKN-GXTWGEPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481203   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM481203(6-((5R,8S)-2-(6-Methylpyridin-2-yl)-5,6,7,8-tetrah...)
Affinity DataIC50:  3nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent