BDBM481603 4-(2-(2-((3'-(5-(2-carboxy- 2-methylpropyl)-1-methyl- 4,5,6,7-tetrahydro-1H- imidazo[4,5-c]pyridine-2- carboxamido)-2,2'-dichloro- [1,1'-biphenyl]-3- yl)carbamoyl)-1-methyl- 1,4,6,7-tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)ethyl)bicyclo[2.2.1]heptane- 1-carboxylic acid::US10906920, Example 21

SMILES Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CC(C)(C)CC(O)=O)CCc3n2C)c1Cl

InChI Key InChIKey=VZOMVPWZDLDEGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481603   

LigandPNGBDBM481603(4-(2-(2-((3'-(5-(2-carboxy- 2-methylpropyl)-1-meth...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
8/22/2021
Entry Details
US Patent