BDBM481788 1-[[3-[2-(4- chlorophenyl)ethyl]-1,2,4- oxadiazol-5-yl]methyl]-6- methyl-7-oxo-pyrazolo[4,3- d]pyrimidine-3-carbonitrile::US10913742, Example 30
SMILES Cn1cnc2c(nn(Cc3nc(CCc4ccc(Cl)cc4)no3)c2c1=O)C#N
InChI Key InChIKey=CXQKCYMIGNQZOZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481788
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 26.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair