BDBM481788 1-[[3-[2-(4- chlorophenyl)ethyl]-1,2,4- oxadiazol-5-yl]methyl]-6- methyl-7-oxo-pyrazolo[4,3- d]pyrimidine-3-carbonitrile::US10913742, Example 30

SMILES Cn1cnc2c(nn(Cc3nc(CCc4ccc(Cl)cc4)no3)c2c1=O)C#N

InChI Key InChIKey=CXQKCYMIGNQZOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481788   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481788(1-[[3-[2-(4- chlorophenyl)ethyl]-1,2,4- oxadiazol-...)
Affinity DataIC50:  26.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent