BDBM481834 5-[(4-oxopyrido[2,3- d]pyrimidin-3-yl)methyl]-3- [rac-(1R,3R)-3-(4- fluorophenyl)cyclopentyl]- 1,3,4-oxadiazol-2-one::US10913742, Example 78
SMILES Fc1ccc(cc1)[C@@H]1CC[C@H](C1)n1nc(Cn2cnc3ncccc3c2=O)oc1=O
InChI Key InChIKey=LPLVBOWGFAEFOE-GDBMZVCRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481834
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 40.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair