BDBM482250 4-benzyl-5,11-dihydro-4H- 3,4,10,11-tetraazadibenzo::US10918645, Example 40::US10918645, Example 54

SMILES O=c1n(Cc2ccccc2)c2nccc3[nH]nc(c23)c2ccccc12

InChI Key InChIKey=SFBMVGVEWIRIRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482250   

LigandPNGBDBM482250(US10918645, Example 54 | 4-benzyl-5,11-dihydro-4H-...)
Affinity DataIC50: 140nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

LigandPNGBDBM482250(US10918645, Example 54 | 4-benzyl-5,11-dihydro-4H-...)
Affinity DataIC50: 6.40E+3nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent