BDBM482268 US10918645, Example 66::US10918645, Example 67

SMILES COc1ccc(Cn2nc3-c4cn(nc4CN(C4CCOCC4)c4nccc2c34)C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=ACVZLKURPPZVCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482268   

LigandPNGBDBM482268(US10918645, Example 66 | US10918645, Example 67)
Affinity DataIC50: 7nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

LigandPNGBDBM482268(US10918645, Example 66 | US10918645, Example 67)
Affinity DataIC50: 26nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent