BDBM482273 2-methyl-9-(tetrahydro-2H-pyran- 4-yl)-2,5,9,10-tetrahydro-1,2,4,5, 8,9-hexaazabenzo[cd]cyclopenta[h]azulene::US10918645, Example 70

SMILES Cn1cc-2c(CN(C3CCOCC3)c3nccc4[nH]nc-2c34)n1

InChI Key InChIKey=JBSRCDXAHJUCCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482273   

LigandPNGBDBM482273(US10918645, Example 70 | 2-methyl-9-(tetrahydro-2H...)
Affinity DataIC50: 23nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent