BDBM482846 5-(3,3- difluoropiperidine- 1-carboxamido)-1- (2-((2R,4R)-4- fluoro-2-((R)-1- hydroxy-2-(6- methylpyridin-2- yl)ethyl)pyrrolidin- 1-yl)-2-oxoethyl)- 1H-indole-3- carboxamide::US10919884, Cmp No. 2::US11649229, Cmp No. 2

SMILES Cc1cccc(CC(O)[C@H]2C[C@@H](F)CN2C(=O)Cn2cc(C(N)=O)c3cc(NC(=O)N4CCCC(F)(F)C4)ccc23)n1

InChI Key InChIKey=VSFZVHRDZJDASO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482846   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM482846(US10919884, Cmp No. 2 | 5-(3,3- difluoropiperidine...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM482846(US10919884, Cmp No. 2 | 5-(3,3- difluoropiperidine...)
Affinity DataIC50: 5.50E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent