BDBM482852 N5- (cyclopropylsulfonyl)- 1-(2-((2S)-5-fluoro-2- ((6-methylpyridin-2- yl)carbamoyl)azepan- 1-yl)-2-oxoethyl)- 1H-indole-3,5- dicarboxamide::US10919884, Cmp No. 8::US11649229, Cmp No. 8

SMILES Cc1cccc(NC(=O)[C@@H]2CCC(F)CCN2C(=O)Cn2cc(C(N)=O)c3cc(ccc23)C(=O)NS(=O)(=O)C2CC2)n1

InChI Key InChIKey=JGCDOVQHQUPPCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482852   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM482852(US10919884, Cmp No. 8 | N5- (cyclopropylsulfonyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM482852(US10919884, Cmp No. 8 | N5- (cyclopropylsulfonyl)-...)
Affinity DataIC50: 5.50E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent