BDBM483491 US10925881, Name (S)-JQ35

SMILES Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCN1CCN(C)CC1)c1nnc(C)n1-2

InChI Key InChIKey=PKQXLRYFPSZKDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483491   

TargetBromodomain-containing protein 4 [349-460](Human)
Tensha Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 483491BDBM483491(US10925881, Name (S)-JQ35)
Affinity DataIC50: 6.13nMAssay Description:The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-167](Human)
Tensha Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 483491BDBM483491(US10925881, Name (S)-JQ35)
Affinity DataIC50: 24.3nMAssay Description:The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent