BDBM483594 N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-yl]-N''-hydroxy-4-({2-[N-(2- hydroxyethyl)-S- methylsulfonimidoyl]ethyl}amino)-1,2,5- oxadiazole-3-carboximidamide (isomer 1)::US10927086, Example 57::US10927086, Example 58
SMILES CS(=O)(CCNc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N/O)=NCCO
InChI Key InChIKey=YDOQIORTBGMJHM-ICMNVNQKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 483594
Affinity DataIC50: 125nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
Affinity DataIC50: 70.6nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair