BDBM483610 4-{[3-(S- aminosulfonimidoyl)propyl]amino}-N- [(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-yl]-N'-hydroxy-1,2,5-oxadiazole- 3-carboximidamide::US10927086, Example 65

SMILES NS(=N)(=O)CCCNc1nonc1\C(N[C@@H]1Cc2ccc(F)cc12)=N/O

InChI Key InChIKey=WQUCBYIMUGSSEK-LLVKDONJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 483610   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483610(4-{[3-(S- aminosulfonimidoyl)propyl]amino}-N- [(7S...)
Affinity DataIC50:  48.2nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent