BDBM483807 4-chloro-1-(4-(3- chloro-5-(pyrimidin- 5-yl)benzyl)- piperazine-1- carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 323::US11655217, Example 323

SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCN(Cc2cc(Cl)cc(c2)-c2cncnc2)CC1

InChI Key InChIKey=MZIFBOBZRYEBPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483807   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483807(US10927105, Ex 323 | 4-chloro-1-(4-(3- chloro-5-(p...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483807(US10927105, Ex 323 | 4-chloro-1-(4-(3- chloro-5-(p...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent