BDBM483808 (R)-1-(2-methyl-4- (2-(pyrrolidin-1-yl)- 4-(trifluoromethyl)- benzyl)piperazine-1- carbonyl)-1H- pyrazole-3- carboxamide::US10927105, Ex 325::US11655217, Example 325

SMILES C[C@@H]1CN(Cc2ccc(cc2N2CCCC2)C(F)(F)F)CCN1C(=O)n1ccc(n1)C(N)=O

InChI Key InChIKey=RDPHHKJPVWYTQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483808   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483808(US10927105, Ex 325 | (R)-1-(2-methyl-4- (2-(pyrrol...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483808(US10927105, Ex 325 | (R)-1-(2-methyl-4- (2-(pyrrol...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent