BDBM483810 (S)-1-(2-methyl-4- (4-(pyrrolidin-1-yl)- 2-(trifluoromethyl)- benzyl)- piperazine-1- carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 329::US11655217, Example 329

SMILES C[C@H]1CN(Cc2ccc(cc2C(F)(F)F)N2CCCC2)CCN1C(=O)n1ccc(n1)C(O)=O

InChI Key InChIKey=BUFWHTGPNBLQRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483810   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483810(US10927105, Ex 329 | (S)-1-(2-methyl-4- (4-(pyrrol...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483810(US10927105, Ex 329 | (S)-1-(2-methyl-4- (4-(pyrrol...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent