BDBM483812 1-(4-((3-(pyrrolidin- 1-yl)-5- (trifluoromethyl)- benzyl)- oxy)piperidine- 1-carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 331::US11655217, Example 331

SMILES OC(=O)c1ccn(n1)C(=O)N1CCC(CC1)OCc1cc(cc(c1)C(F)(F)F)N1CCCC1

InChI Key InChIKey=ZRZNAGYOARGRSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483812   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483812(US10927105, Ex 331 | 1-(4-((3-(pyrrolidin- 1-yl)-5...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483812(US10927105, Ex 331 | 1-(4-((3-(pyrrolidin- 1-yl)-5...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent