BDBM483820 1-(trans-5-((4- chloro-3-(thiazol-2- yl)benzyl)oxy)- octahydrocyclopenta- [c]pyrrole-2- carbonyl)- 1H-pyrazole-3- carboxylic acid::US10927105, Ex 345::US11655217, Example 345

SMILES OC(=O)c1ccn(n1)C(=O)N1C[C@@H]2C[C@H](C[C@@H]2C1)OCc1ccc(Cl)c(c1)-c1nccs1

InChI Key InChIKey=UQXZDOAAAOAECH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483820   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483820(US10927105, Ex 345 | 1-(trans-5-((4- chloro-3-(thi...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483820(US10927105, Ex 345 | 1-(trans-5-((4- chloro-3-(thi...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent