BDBM483821 1-(4-(3-(4- chlorophenoxy)-5- fluorobenzyl)- piperazine-1- carbonyl)-4- methyl-1H- pyrazole-3- carboxylic acid::US10927105, Ex 346::US11655217, Example 346

SMILES Cc1cn(nc1C(O)=O)C(=O)N1CCN(Cc2cc(F)cc(Oc3ccc(Cl)cc3)c2)CC1

InChI Key InChIKey=BPFWANLLLFSZAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483821   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483821(US10927105, Ex 346 | 1-(4-(3-(4- chlorophenoxy)-5-...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483821(US10927105, Ex 346 | 1-(4-(3-(4- chlorophenoxy)-5-...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent