BDBM483839 (S)-1-(2-methyl-4- (3-((4- (trifluoromethyl)- pyridin-2- yl)oxy)benzyl)- piperazine-1- carbonyl)- 1H-pyrazole-3- carboxylic acid::US10927105, Ex 373::US11655217, Example 373

SMILES C[C@H]1CN(Cc2cccc(Oc3cc(ccn3)C(F)(F)F)c2)CCN1C(=O)n1ccc(n1)C(O)=O

InChI Key InChIKey=XPMLHOZBXTWRJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483839   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483839(US10927105, Ex 373 | (S)-1-(2-methyl-4- (3-((4- (t...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483839(US10927105, Ex 373 | (S)-1-(2-methyl-4- (3-((4- (t...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent