BDBM483850 1-(1-(6- (trifluoromethyl)- benzo- [b]thiophene-2- carbonyl)-1,8- diazaspiro- [4.5]decane-8- carbonyl)-1H- pyrazole-3- carboxamide::US10927105, Ex 389::US11655217, Example 389

SMILES NC(=O)c1ccn(n1)C(=O)N1CCC2(CCCN2C(=O)c2cc3ccc(cc3s2)C(F)(F)F)CC1

InChI Key InChIKey=FNLOQIKIPDSJDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483850   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483850(US10927105, Ex 389 | 1-(1-(6- (trifluoromethyl)- b...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483850(US10927105, Ex 389 | 1-(1-(6- (trifluoromethyl)- b...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent