BDBM483854 1-(5-(4-(4- hydroxytetrahydro- 2H-pymn-4-yl)-2- (trifluoromethyl)- benzyl)- octahydropyrrolo- [3,4-c]pyrrole-2- carbonyl)-1H- pyrazole-3- carboxamide::US10927105, Ex 396::US11655217, Example 396

SMILES NC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3ccc(cc3C(F)(F)F)C3(O)CCOCC3)CC2C1

InChI Key InChIKey=QAXMYVKZJZYRPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483854   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483854(US10927105, Ex 396 | 1-(5-(4-(4- hydroxytetrahydro...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483854(US10927105, Ex 396 | 1-(5-(4-(4- hydroxytetrahydro...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent