BDBM483876 1-(7-(4-morpholino- 2-(trifluoromethyl)- benzyl)-2,7- diazaspiro- [4.4]nonane-2- carbonyl)-1H- pyrazole-3- carboxamide::US10927105, Ex 436::US11655217, Example 436

SMILES NC(=O)c1ccn(n1)C(=O)N1CCC2(CCN(Cc3ccc(cc3C(F)(F)F)N3CCOCC3)C2)C1

InChI Key InChIKey=URZNJNRGYKQIOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483876   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483876(US10927105, Ex 436 | 1-(7-(4-morpholino- 2-(triflu...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483876(US10927105, Ex 436 | 1-(7-(4-morpholino- 2-(triflu...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent