BDBM4840 1-(2-amino-6-{3-[2-(diethylamino)ethoxy]-2,6-dimethylphenyl}pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea::PD089828 analog 21

SMILES CCN(CC)CCOc1ccc(C)c(c1C)-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C

InChI Key InChIKey=PWESNWJNRDIXTH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 4840   

TargetPlatelet-derived growth factor receptor beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM4840(1-(2-amino-6-{3-[2-(diethylamino)ethoxy]-2,6-dimet...)
Affinity DataIC50:  1.18E+4nMpH: 7.4 T: 25°CAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM4840(1-(2-amino-6-{3-[2-(diethylamino)ethoxy]-2,6-dimet...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibitory activity against platelet-derived growth factor receptorMore data for this Ligand-Target Pair
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM4840(1-(2-amino-6-{3-[2-(diethylamino)ethoxy]-2,6-dimet...)
Affinity DataIC50:  1.65E+3nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labeled ATP to the poly (E: Y) subs...More data for this Ligand-Target Pair
In DepthDetails Article
TargetFibroblast growth factor receptor 1(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM4840(1-(2-amino-6-{3-[2-(diethylamino)ethoxy]-2,6-dimet...)
Affinity DataIC50:  890nMAssay Description:The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labeled ATP to the poly (E: Y) subs...More data for this Ligand-Target Pair
In DepthDetails Article