BDBM484052 (S)-1-((R)-8-(4'-(1- aminocyclopropyl)-6- methoxybiphenyl-3- ylsulfonyl)-1-oxa-8- azaspiro[4.5]decan-3- ylamino)-3-(3-(1- (hydroxymethyl) cyclopropylsulfonyl (phenoxy)propan-2-ol::US10927123, Compound 199

SMILES COc1ccc(cc1-c1ccc(cc1)C1(N)CC1)S(=O)(=O)N1CCC2(C[C@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)C2(CO)CC2)CC1

InChI Key InChIKey=RZPQETZWVOXDNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484052   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484052((S)-1-((R)-8-(4'-(1- aminocyclopropyl)-6- methoxyb...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent