BDBM484063 (S)-1-(3-(1- (hydroxymelhyl) cyclopropylsulfonyl) phenoxy)-3-((S)-8-(4'- ((tertpentylamino) melhyl)biphenyl-3- ylsulfonyl)-1-oxa-8- azaspiro[4.5]decan-3- ylamino)propan-2-ol::US10927123, Compound 241

SMILES CCC(C)(C)NCc1ccc(cc1)-c1cccc(c1)S(=O)(=O)N1CCC2(C[C@@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)C2(CO)CC2)CC1

InChI Key InChIKey=AIZVEJXGKOPKCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484063   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484063((S)-1-(3-(1- (hydroxymelhyl) cyclopropylsulfonyl) ...)
Affinity DataIC50: 2.11E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent