BDBM484064 (S)-1-((S)-8-(4'- (azetidin-1- ylmethyl)biphenyl-3- ylsulfonyl)-1-oxa-8- azaspiro[4.5]decan-3- ylamino)-3-(3-(1- (hydroxymethyl) cyclopropylsulfonyl) phenoxy)propan-2-ol::US10927123, Compound 243

SMILES OCC1(CC1)S(=O)(=O)c1cccc(OC[C@@H](O)CN[C@@H]2COC3(C2)CCN(CC3)S(=O)(=O)c2cccc(c2)-c2ccc(CN3CCC3)cc2)c1

InChI Key InChIKey=FEJYSMWXFZDMFI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484064   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484064((S)-1-((S)-8-(4'- (azetidin-1- ylmethyl)biphenyl-3...)
Affinity DataIC50: 3.50E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent