BDBM484182 8-(2-(3-fluoropyridin-2- yl)ethyl)-12-isopentyl-4-oxa- 8,12- diazadispiro[2.1.5.3]tridecane::US10927128, Example 103::US11649248, Example 103

SMILES CC(C)CCN1CC2(CC2)OC2(CCN(CCc3ncccc3F)CC2)C1

InChI Key InChIKey=UCFMZNBHCGXLCY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484182   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484182(8-(2-(3-fluoropyridin-2- yl)ethyl)-12-isopentyl-4-...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP-4 complex subunit sigma-1(Homo sapiens (Human))
Esteve Pharmaceuticals.

US Patent
LigandPNGBDBM484182(8-(2-(3-fluoropyridin-2- yl)ethyl)-12-isopentyl-4-...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent