BDBM484625 US10934297, Compound 19::US11713320, Compound 19

SMILES FC1(F)CCC(CC1)NC(=O)c1n[nH]c2ccc(cc12)-c1cnn(c1)C1CC1

InChI Key InChIKey=VQHOJFTXMGMEHA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 484625   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM484625(US10934297, Compound 19 | US11713320, Compound 19)
Affinity DataEC50:  117nMAssay Description:DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM484625(US10934297, Compound 19 | US11713320, Compound 19)
Affinity DataEC50:  64nMAssay Description:Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM484625(US10934297, Compound 19 | US11713320, Compound 19)
Affinity DataEC50:  117nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM484625(US10934297, Compound 19 | US11713320, Compound 19)
Affinity DataEC50:  64nMAssay Description:GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent