BDBM484650 Preparation of N-((2S,4R)-1-(2-fluoro-2-methylpropyl)-2-methylpiperidin-4-yl)-5-(1-methyl-1H-pyrazol-4-yl)-1H-indazole-3-carboxamide ::US10934297, Compound 44::US11713320, Compound 44
SMILES C[C@H]1CC(CCN1CC(C)(C)F)NC(=O)c1n[nH]c2ccc(cc12)-c1cnn(C)c1
InChI Key
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 484650
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed
US Patent
Samumed
US Patent
Affinity DataEC50: 7nMAssay Description:DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed
US Patent
Samumed
US Patent
Affinity DataEC50: 7nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves ...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...More data for this Ligand-Target Pair