BDBM484650 Preparation of N-((2S,4R)-1-(2-fluoro-2-methylpropyl)-2-methylpiperidin-4-yl)-5-(1-methyl-1H-pyrazol-4-yl)-1H-indazole-3-carboxamide ::US10934297, Compound 44::US11713320, Compound 44

SMILES C[C@H]1CC(CCN1CC(C)(C)F)NC(=O)c1n[nH]c2ccc(cc12)-c1cnn(C)c1

InChI Key

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 484650   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM484650(Preparation of N-((2S,4R)-1-(2-fluoro-2-methylprop...)
Affinity DataEC50:  7nMAssay Description:DYRK1A: Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM484650(Preparation of N-((2S,4R)-1-(2-fluoro-2-methylprop...)
Affinity DataEC50:  7nMAssay Description:Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM484650(Preparation of N-((2S,4R)-1-(2-fluoro-2-methylprop...)
Affinity DataEC50:  7nMAssay Description:Each compound was dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Biosplice Therapeutics

US Patent
LigandPNGBDBM484650(Preparation of N-((2S,4R)-1-(2-fluoro-2-methylprop...)
Affinity DataEC50:  7nMAssay Description:GSK3β: Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-respo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent