BDBM485696 (S) N-(4-(2-bromo-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzyloxy)-5-chloro-2-(3-cyanobenzyloxy)benzyl) pipecolinic acid::US10941129, Example 24

SMILES OC(=O)[C@@H]1CCCCN1Cc1cc(Cl)c(OCc2cccc(c2Br)-c2ccc3OCCOc3c2)cc1OCc1cccc(c1)C#N

InChI Key InChIKey=BRLDDPSGYFSHLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485696   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485696((S) N-(4-(2-bromo-3-(2,3-dihydrobenzo[b][1,4]dioxi...)
Affinity DataIC50: 67.5nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent