BDBM4863 1-(4-Chloroanilino)-4-(4-pyridylmethyl)-6-methylphthalazine and 1-(4-Chloroanilino)-4-(4-pyridylmethyl)-7-methylphthalazine Dihydrochloride::CGP79787 Analog 46::N-(4-chlorophenyl)-7-methyl-4-(pyridin-4-ylmethyl)phthalazin-1-amine

SMILES Cc1ccc2c(Cc3ccncc3)nnc(Nc3ccc(Cl)cc3)c2c1

InChI Key InChIKey=YVMDSPWVEDPXJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4863   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 4863BDBM4863(1-(4-Chloroanilino)-4-(4-pyridylmethyl)-6-methylph...)
Affinity DataIC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 4863BDBM4863(1-(4-Chloroanilino)-4-(4-pyridylmethyl)-6-methylph...)
Affinity DataIC50: 4.70E+3nMAssay Description:The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2005
Entry Details Article
PubMed