BDBM486522 US10947251, Example 4
SMILES COc1cc(c(F)cc1N1[C@H]2CCN(C[C@@H]2OCC1=O)S(=O)(=O)Nc1ccon1)-c1cccc(c1)C(F)(F)F
InChI Key InChIKey=HLTZYGSBNPVIGB-RXVVDRJESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 486522
Affinity DataIC50: 3.52nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Heterologously Express hNav1.7 and the β1 SubunitPreparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant...More data for this Ligand-Target Pair