BDBM486557 US10947251, Example 30
SMILES [H][C@]12CN(CC[C@]1([H])N(C(=O)CO2)c1cc(F)c(cc1OC)-c1cccc(OC(F)(F)F)c1)S(=O)(=O)Nc1ccon1
InChI Key InChIKey=XXHDUUWMSHLIFT-RXVVDRJESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 486557
Affinity DataIC50: 2.35nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Affinity DataIC50: 35.6nMAssay Description:Heterologously Express hNav1.7 and the β1 SubunitPreparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant...More data for this Ligand-Target Pair