BDBM487192 2-Benzyl-3-(4-chloro-phenyl)-5-propyl-4H-pyrazolo[1,5-a]pyrimidin-7-one::US10953012, Example 18

SMILES CCCc1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(Cl)cc3)c2[nH]1

InChI Key InChIKey=KLZVFZOSQNKUSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487192   

TargetPAS domain-containing serine/threonine-protein kinase [879-1323](Homo sapiens (Human))
Bioenergenix

US Patent
LigandPNGBDBM487192(2-Benzyl-3-(4-chloro-phenyl)-5-propyl-4H-pyrazolo[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In DepthDetails US Patent