BDBM487217 US10947254, Example 1-57

SMILES COc1cccc(C[C@@H]2COc3ccc4ncc(F)cc4c3C(=O)N[C@H](C(=O)NCCn3ncc(OC)n3)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@H](CC(F)(F)F)C(=O)N2)c1

InChI Key InChIKey=JWTVAKXJTWBBHW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487217   

TargetCytochrome P450 3A4(Human)
Idorsia Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 487217BDBM487217(US20260098060, Example 50)
Affinity DataIC50: 2.40E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent