BDBM487303 US10947254, Example 5-25

SMILES COc1cc(CCNC(=O)[C@@H]2CC(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@H](CC(C)(F)F)C(=O)N[C@H](Cc3cccc(OC)n3)COc3ccc4ncc(F)cc4c3C(=O)N2)on1

InChI Key InChIKey=XANXRIVEMGLDRP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487303   

TargetCytochrome P450 3A4(Human)
Idorsia Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 487303BDBM487303(US20260098060, Example 55)
Affinity DataIC50: 730nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2026
Entry Details
US Patent