BDBM488162 (E)-2-(5-(cyclopropylmethyl)-4- (3-fluoro-4- sulfamoylbenzyl)-3-(3- (2-(5-methylthiophen-2- yl)vinyl)phenyl)-1H- pyrazol-1-yl)thiazole-4- carboxylic acid::US10954228, Compound 119

SMILES Cc1ccc(\C=C\c2cccc(c2)-c2nn(c(CC3CC3)c2Cc2ccc(c(F)c2)[SH+](N)=O)-c2nc(cs2)C(O)=O)s1

InChI Key InChIKey=XCBQPWGWFUTGHG-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488162   

TargetL-lactate dehydrogenase A chain(Human)
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488162((E)-2-(5-(cyclopropylmethyl)-4- (3-fluoro-4- sulfa...)
Affinity DataIC50: 100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent