BDBM488239 2-(5-(cyclopropylmethyl)-3-(3'- (dimethylamino)-6- fluoro-[1,1'-biphenyl]-3- yl)-4-(3-fluoro-4- sulfamoylbenzyl)- 1H-pyrazol-1-yl)thiazole-4- carboxylic acid::US10954228, Compound 194::US11752138, Compound 194

SMILES CN(C)c1cccc(c1)-c1cc(ccc1F)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)S(N)(=O)=O)-c1nc(cs1)C(O)=O

InChI Key InChIKey=QAFHBOUWRGDMHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488239   

TargetL-lactate dehydrogenase B chain(Human)
Vanderbilt University

US Patent
LigandPNGBDBM488239(2-(5-(cyclopropylmethyl)-3-(3'- (dimethylamino)-6-...)
Affinity DataIC50: 100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent

TargetL-lactate dehydrogenase A chain(Human)
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488239(2-(5-(cyclopropylmethyl)-3-(3'- (dimethylamino)-6-...)
Affinity DataIC50: 100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent