BDBM488264 2-(5-(cyclopropylmethyl)-4-(3- fluoro-4-sulfamoylbenzyl)- 3-(4'-(trifluoromethyl)-[1,1'- biphenyl]-3-yl)-1H-pyrazol-1- yl)thiazole-4-carboxylic acid::US10954228, Compound 219::US11752138, Compound 219

SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2cccc(c2)-c2ccc(cc2)C(F)(F)F)-c2nc(cs2)C(O)=O)cc1F

InChI Key InChIKey=OZQLGEXLOYRETL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488264   

TargetL-lactate dehydrogenase A chain(Human)
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488264(2-(5-(cyclopropylmethyl)-4-(3- fluoro-4-sulfamoylb...)
Affinity DataIC50: 100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetL-lactate dehydrogenase B chain(Human)
Vanderbilt University

US Patent
LigandPNGBDBM488264(2-(5-(cyclopropylmethyl)-4-(3- fluoro-4-sulfamoylb...)
Affinity DataIC50: 100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent