BDBM488292 2-(5-(cyclopropylmethyl)- 4-(3-fluoro-4- sulfamoylbenzyl)-3- (3-((5-methylthiophen-2- yl)ethynyl)phenyl)-1H- pyrazol-1-yl)oxazole-4- carboxylic acid::US10954228, Compound 247::US11752138, Compound 247

SMILES Cc1ccc(s1)C#Cc1cccc(c1)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)S(N)(=O)=O)-c1nc(co1)C(O)=O

InChI Key InChIKey=DMXWHRUXPNXXHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488292   

TargetL-lactate dehydrogenase A chain(Human)
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488292(2-(5-(cyclopropylmethyl)- 4-(3-fluoro-4- sulfamoyl...)
Affinity DataIC50: 100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetL-lactate dehydrogenase B chain(Human)
Vanderbilt University

US Patent
LigandPNGBDBM488292(2-(5-(cyclopropylmethyl)- 4-(3-fluoro-4- sulfamoyl...)
Affinity DataIC50: 100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent