BDBM488320 US10954240, Example 24

SMILES CCc1nnc2CN(CCn12)c1cc(ccn1)-n1ncc2ccc(OC(C)C)cc12

InChI Key InChIKey=DWBCRUGLPCMHAD-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488320   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527,G2019S](Human)
Merck Sharp & Dohme

US Patent

LigandBDBM488320(US10954240, Example 24)Copy SMILESCopy InChI

Affinity DataIC50: 435nMAssay Description:LRRK2 Km ATP LanthaScreen Assaya) 400 nl of a 1:2.15 serial dilution of test compound (98 μM top assay concentration) is spotted via Labcyte Ech...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/28/2021
Entry Details
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