BDBM488472 US10954243, Example 3

SMILES CC1(N)CCN(c2nc3[nH]nc(-c4cccc(Cl)c4Cl)c3nc2O)CC1

InChI Key InChIKey=VTRXMYATXKKBOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488472   

LigandChemical structure of BindingDB Monomer ID 488472BDBM488472(US10954243, Example 3)
Affinity DataIC50: 960nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent