BDBM488575 US10961198, Compound 2::trans-N-((trans-4-(3-Cyano-4-methoxyphenyl)cyclohexyl)methyl)-N-(3-(1-ethyl-1H-pyrazol-4-yl)phenyl)-4-hydroxycyclohexanecarboxamide

SMILES CCn1cc(cn1)-c1cccc(c1)N(C[C@H]1CC[C@@H](CC1)c1ccc(OC)c(c1)C#N)C(=O)[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=GBGWXZSKWIMHFY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488575   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488575(US10961198, Compound 2 | trans-N-((trans-4-(3-Cyan...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent