BDBM488577 US10961198, Compound 2.02::trans-N-(3-(1-Ethyl-1H-pyrazol-4-yl)phenyl)-4-hydroxy-N- ((trans-4-(4-methoxy-3- methylphenyl)cyclohexyl)methyl)cyclohexanecarboxamide

SMILES CCn1cc(cn1)-c1cccc(c1)N(C[C@H]1CC[C@@H](CC1)c1ccc(OC)c(C)c1)C(=O)[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=BAZCVICKJZJFEG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488577   

TargetBile acid receptor(Human)
Metacrine

US Patent
LigandPNGBDBM488577(US10961198, Compound 2.02 | trans-N-(3-(1-Ethyl-1H...)
Affinity DataEC50: <250nMAssay Description:After 18 h of incubation, the medium in the T175 flask was changed with fresh DMEM+10% charcoal super-stripped serum. In a polypropylene tube, 2500 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
US Patent